Endocrine Abstracts

Aim: We explored the mechanistic interactions and potential therapeutic benefits of curcumin and quercetin co-administration with a specific focus on Glycogen synthase kinase 3 GSK-3 activity.Methods: We hypothesize that excess GSK-3 accumulation in the substantia nigra is driven by oxidative stress and aim to test the effects of these compounds on the localization and activity of GSK-3 in the well-established model organism Drosophila melanogaster. We p...